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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YWHAZ
All Species:
54.55
Human Site:
S57
Identified Species:
85.71
UniProt:
P63104
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63104
NP_001129171.1
245
27745
S57
N
V
V
G
A
R
R
S
S
W
R
V
V
S
S
Chimpanzee
Pan troglodytes
XP_528202
382
42115
S194
N
V
V
G
A
R
R
S
S
W
R
V
V
S
S
Rhesus Macaque
Macaca mulatta
XP_001098275
578
62565
S390
N
V
V
G
A
R
R
S
S
W
R
V
V
S
S
Dog
Lupus familis
XP_850323
289
32637
S101
N
V
V
G
A
R
R
S
S
W
R
V
V
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQV8
246
28068
S59
N
V
V
G
A
R
R
S
S
W
R
V
I
S
S
Rat
Rattus norvegicus
P63102
245
27753
S57
N
V
V
G
A
R
R
S
S
W
R
V
V
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509087
339
37959
S57
N
V
V
G
A
R
R
S
S
W
R
V
V
S
S
Chicken
Gallus gallus
Q5ZKC9
245
27757
S57
N
V
V
G
A
R
R
S
S
W
R
V
V
S
S
Frog
Xenopus laevis
Q91896
245
27711
S57
N
V
V
G
A
R
R
S
S
W
R
V
V
S
S
Zebra Danio
Brachydanio rerio
Q5PRD0
244
27628
S57
N
V
V
G
A
R
R
S
S
W
R
V
I
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29310
248
28209
S60
N
V
V
G
A
R
R
S
S
W
R
V
I
S
S
Honey Bee
Apis mellifera
XP_391841
247
28058
S59
N
V
V
G
A
R
R
S
S
W
R
V
I
S
S
Nematode Worm
Caenorhab. elegans
Q20655
248
28049
S59
N
V
V
G
A
R
R
S
S
W
R
V
I
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q01525
259
29143
W63
I
G
A
R
R
A
S
W
R
I
I
S
S
I
E
Baker's Yeast
Sacchar. cerevisiae
P34730
273
31043
R62
G
A
R
R
A
S
W
R
I
V
S
S
I
E
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.1
42.3
84
N.A.
86.5
99.5
N.A.
71.9
99.1
89.3
86.9
N.A.
80.6
82.5
80.2
N.A.
Protein Similarity:
100
64.1
42.3
84
N.A.
93.5
99.5
N.A.
71.9
100
94.6
94.6
N.A.
89.1
91
89.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
100
100
100
93.3
N.A.
93.3
93.3
93.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
100
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
62.5
60.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
72.9
72.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
94
7
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
0
87
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
7
7
7
0
40
7
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
87
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
7
14
7
87
87
7
7
0
87
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
7
87
87
0
7
14
7
87
87
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
87
87
0
0
0
0
0
0
7
0
87
54
0
0
% V
% Trp:
0
0
0
0
0
0
7
7
0
87
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _